Cholecalciferol assessment in the oral cavity
DOI:
https://doi.org/10.35381/s.v.v8i1.4083Keywords:
Colecalciferol, oral health, mouth diseases, (Source: DeCS)Abstract
Objective: To study the evaluation of cholecalciferol in the oral cavity. Method: Descriptive documentary. Conclusion: Cholecalciferol, or vitamin D3, plays a fundamental role in oral health, showing significant benefits in immune modulation, periodontal health and prevention of oral pathologies, including cancer. Evidence suggests that its deficiency is associated with an increased risk of oral diseases, underscoring the importance of maintaining adequate levels of this vitamin. Although its therapeutic use presents promising benefits, it is crucial to establish well-defined clinical protocols to maximize its efficacy and minimize possible side effects. Cholecalciferol is emerging as a valuable agent in contemporary dentistry, with considerable potential to improve oral health through evidence-based preventive and therapeutic strategies.
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References
Verma A, Vincent-Chong VK, DeJong H, Hershberger PA, Seshadri M. Impact of dietary vitamin D on initiation and progression of oral cancer. J Steroid Biochem Mol Biol. 2020;199:105603. https://n9.cl/nhnw5
Arponen H, Waltimo-Sirén J, Hauta-Alus HH, et al. Effects of a 2-Year Early Childhood Vitamin D3 Intervention on Tooth Enamel and Oral Health at Age 6-7 Years. Horm Res Paediatr. 2023;96(4):385-394. https://n9.cl/zr871
Hung M, Almpani K, Thao B, Sudweeks K, Lipsky MS. Vitamin D in the Prevention and Treatment of Oral Cancer: A Scoping Review. Nutrients. 2023;15(10):2346. https://doi.org/10.3390/nu15102346
Ślebioda Z, Szponar E, Dorocka-Bobkowska B. Vitamin D and Its Relevance in the Etiopathogenesis of Oral Cavity Diseases. Arch Immunol Ther Exp (Warsz). 2016;64(5):385-397. https://doi.org/10.1007/s00005-016-0384-z
Cagetti MG, Wolf TG, Tennert C, Camoni N, Lingström P, Campus G. The Role of Vitamins in Oral Health. A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2020;17(3):938. https://doi.org/10.3390/ijerph17030938
Shah M, Poojari M, Nadig P, et al. Vitamin D and Periodontal Health: A Systematic Review. Cureus. 2023;15(10):e47773. https://doi.org/10.7759/cureus.47773
Tada H, Shimizu T, Nagaoka I, Takada H. Vitamin D3 analog maxacalcitol (OCT) induces hCAP-18/LL-37 production in human oral epithelial cells. Biomed Res. 2016;37(3):199-205. https://n9.cl/fj7ix
Küchler EC, Schröder A, Teodoro VB, et al. The role of 25-hydroxyvitamin-D3 and vitamin D receptor gene in human periodontal ligament fibroblasts as response to orthodontic compressive strain: an in vitro study. BMC Oral Health. 2021;21(1):386. https://n9.cl/n7stc
Oteri G, Cicciù M, Peditto M, et al. Does Vitamin D3 Have an Impact on Clinical and Biochemical Parameters Related to Third Molar Surgery. J Craniofac Surg. 2016;27(2):469-476. https://n9.cl/lolix
Yuan FN, Valiyaparambil J, Woods MC, et al. Vitamin D signaling regulates oral keratinocyte proliferation in vitro and in vivo. Int J Oncol. 2014;44(5):1625-1633. https://doi.org/10.3892/ijo.2014.2338
Zhang C, Liu K, Hou J. Extending the vitamin D pathway to vitamin D3 and CYP27A1 in periodontal ligament cells. J Periodontol. 2021;92(7):44-53. https://n9.cl/thpkfu
Navya S, Prashantha GS, Sabrish S, Roshan MS, Mathew S. Evaluation of the effect of local administration of PRP vs vitamin D3 on the rate of orthodontic tooth movement and the associated external apical root resorption [published correction appears in J Oral Biol Craniofac Res. 2024;14(4):351-352. https://n9.cl/pdg9i5.
Sanaei M, Banasiri M, Shafiee G, et al. Calcium vitamin D3 supplementation in clinical practice: side effect and satisfaction [published correction appears in J Diabetes Metab Disord. 2017;18:16-39. https://n9.cl/p3pxrq.
Thum-Tyzo KJ, Tyzo BJ, Chałas R. Oral lichen planus among patients from Lublin Region in relation to 25-hydroxy-vitamin D3 serum level. Ann Agric Environ Med. 2024;31(1):138-143. https://doi.org/10.26444/aaem/169166
Oak ASW, Bocheva G, Kim TK, et al. Noncalcemic Vitamin D Hydroxyderivatives Inhibit Human Oral Squamous Cell Carcinoma and Down-regulate Hedgehog and WNT/β-Catenin Pathways. Anticancer Res. 2020;40(5):2467-2474. https://n9.cl/yy5qv
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