Beta-2 microglobulin for detection of kidney disease in the association of the elderly

Abstract

Renal disease is the final result of a series of pathological situations that cause irreversible damage to the kidney, ending in a progressive loss of renal function, which usually has lethal consequences if the patient does not receive dialysis treatment or a transplant. According to the World Health Organization, it is an important cause of death and disability and it estimates that its tendency will grow exponentially, fundamentally among vulnerable populations, presenting itself as a threat to public health. The objective of this study was to determine the prevalence of kidney disease in the members of the Association of Elders of the Jipijapa Canton, by analyzing blood concentration indicators of the Beta-2 Microglobulin polypeptide, by turbidimetric methods; and to relate it to the risk factors associated with the deterioration of renal function, which were revealed in the consultations of habits performed on these elderly people, as a prophylactic action and early detection of the disease. A descriptive cross-sectional method was used, based on a probabilistic sampling that included 49 individuals with an average age of 71 years, who underwent examinations and surveys. The data was collected in a registration form and processed in SPSS for analysis. Despite the fact that 75.5% of the subjects reflected acceptable values in the Beta-2 Microglobulin tests, it can not be ruled out that the rest presented results considered superior to the normal, corroborating the initial hypothesis that more than 15% of the population. The study had high concentrations of the molecules under study, which indicates that they developed kidney disease. The main associated risk factors detected correspond, in order of priority, to arterial hypertension and type 2 diabetes mellitus. The relationship between the risk exposure and the results of the test confirmed its influence and the harmful effect on those affected.