Initial fluid therapy in the treatment of acute pancreatitis

Authors

DOI:

https://doi.org/10.35381/s.v.v9i17.4334

Keywords:

Initial fluid therapy, isotonic/colloid solutions, acute pancreatitis, aggressive fluid therapy, (Source: DeCS).

Abstract

Objective: To determine the initial fluid therapy of choice in patients diagnosed with acute pancreatitis. Method: A descriptive design type of literature review was used with inclusion criteria in articles of scientific journals in databases such as: Redalyc, Scielo, PubMed/Medline, Web of Science and Scopus. The Prisma method was used to classify, identify eligibility criteria. Results: The use of Ringer's lactate in the management of acute pancreatitis is considered beneficial in the studies analyzed with statistically significant results that highlight shorter hospital stay, risk of admission to intensive care and progression to complications or severity. Conclusion: The best fluid to treat this pathology is ringer lactate and the infusion volume should be around 2,500 - 4,000 milliliters in 24 hours. Because aggressive hydration predisposes to the development of renal failure and acute respiratory failure with mechanical ventilatory support.

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References

Mizrahi JD, Surana R, Valle JW, Shroff RT. Pancreatic cancer. The Lancet. 2020;395(10242):2008-2020. https://doi.org/10.1016/S0140-6736(20)30974-0

Salazar D, Morejón C. Fluidoterapia en pancreatitis aguda. Revista científica INSPILIP. 2022;6(Esp):1-14. https://doi.org/10.31790/inspilip.v6iEspecial.321

Richardson A, Park WG. Acute pancreatitis and diabetes mellitus: a review. Korean J Intern Med. 2021;36(1):15-24. https://doi.org/10.3904/kjim.2020.505

Russo Lozano J, Ochoa Sánchez B, Oñate Silva I, Espinoza Díaz C, Pérez Aldas D, Rivadeneira Campoverde J, et al. Incidencia y características epidemiológicas de la pancreatitis aguda en el Hospital General Ambato del IESS, Ecuador. AVFT – Archivos Venezolanos de Farmacología y Terapéutica. 2020;39(4):264-267. https://n9.cl/e3u0h

Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Clasificación de la pancreatitis aguda--2012: revisión de la clasificación de Atlanta y definiciones por consenso internacional. Gut. 2012;62(1):102-111. https://doi.org/10.1136/gutjnl-2012-302779

Mancilla Asencio C, Berger Fleiszig Z. Intra-Abdominal Hypertension: A Systemic Complication of Severe Acute Pancreatitis. Medicina. 2022;58(6):785. https://doi.org/10.3390/medicina58060785

Yang D, Kang J, Li Y, Wen C, Yang S, Ren Y, et al. Development of a predictive nomogram for acute respiratory distress syndrome in patients with acute pancreatitis complicated with acute kidney injury. Renal Failure. 2023;45(2):2251591. https://doi.org/10.1080/0886022X.2023.2251591

Crosignani A, Spina S, Marrazzo F, Cimbanassi S, Malbrain MLNG, Regenmortel NV, et al. Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review. Ann. Intensive Care. 2022;12(1):98. https://doi.org/10.1186/s13613-022-01072-y

Gomes CA, Di Saverio S, Sartelli M, Segallini E, Cilloni N, Pezzilli R, et al. Severe acute pancreatitis: eight fundamental stepsrevised according to the ‘PANCREAS’ acronym. The Annals of The Royal College of Surgeons of England. 2020;102(8):555-559. https://doi.org/10.1308/rcsann.2020.0029

Kumar A, Bhatia M. Role of Hydrogen Sulfide, Substance P and Adhesion Molecules in Acute Pancreatitis. Int. J. Mol. Sci. 2021;22(22):12136. https://doi.org/10.3390/ijms222212136

Yewale R, Chand N, Ramakrishna BS. Prediction of Severity Outcomes in Acute Pancreatitis. An Odyssey in Eternal Evolution. Gastroenterology, Hepatology and Endoscopy Practice. 2022;2(4):143-151. https://doi.org/10.4103/ghep.ghep_24_22

Lee DW, Cho CM. Predicting severity of acute pancreatitis. Medicina. 2022;58(6):787. https://doi.org/10.3390/medicina58060787

Karki B, Thapa S, Khadka D, Karki S, Shrestha R, Khanal A, et al. Intravenous Ringers lactate versus normal saline for predominantly mild acute pancreatitis in a Nepalese Tertiary Hospital. PLoS One. 2022;17(1):e0263221. https://doi.org/10.1371/journal.pone.0263221

Bharmal SH, Kimita W, Ko J, Petrov MS. Cytokine signature for predicting new-onset prediabetes after acute pancreatitis: A prospective longitudinal cohort study. Cytokine. 2022;150:155768. https://doi.org/10.1016/j.cyto.2021.155768

Guidi M, Curvale C, Pasqua A, Hwang HJ, Pires H, Basso S, et al. Actualización en el manejo inicial de la pancreatitis aguda. Acta Gastroenterol Latinoam. 2019;49(4):307-323. https://n9.cl/uqih4

Bartel M. Pancreatitis aguda. [Online]. 2022. https://n9.cl/kcy72

Severino A, Varca S, Airola C, Mezza T, Gasbarrini A, Franceschi F, et al. Antibiotic Utilization in Acute Pancreatitis: A Narrative Review. Antibiotics. 2023;12(7):1120. https://doi.org/10.3390/antibiotics12071120

Ke L, Mao W, Li W. Managing Organ Failure in Acute Pancreatitis. In Windsor JA, Barreto SG, Phillips ARJ. Acute Pancreatitis. Springer; 2024. (pp. 235-251). https://doi.org/10.1007/978-981-97-3132-9_17

Méndez López I. Uso de la fluidoterapia en la práctica clínica. Bol Inf Farmacoter Navar. 2023;31(3):1-26. https://doi.org/10.54095/BITN20233103

González Zambrana RJ. Evolución y manejo de la Pancreatitis Aguda de origen Biliar en pacientes ingresados en el departamento de Cirugía del HEODRA en el período enero 2019 - diciembre 2021. (Tesis de especialidad) Departamento de Cirugía General, Universidad Nacional Autónoma de Nicaragua, León, Nicaragua; 2022. https://n9.cl/ncmve

Lee PJ, Papachristou GI. New insights into acute pancreatitis. Nat Rev Gastroenterol Hepatol. 2019;16:479-496. https://doi.org/10.1038/s41575-019-0158-2

Yamashita T, Horibe M, Sanui M, Sasaki M, Sawano H, Goto T, et al. Large Volume Fluid Resuscitation for Severe Acute Pancreatitis is Associated With Reduced Mortality: A Multicenter Retrospective Study. Journal of Clinical Gastroenterology. 2019;53(5):385-391. https://doi.org/10.1097/MCG.0000000000001046

De Waele E, Malbrain MLNG, Spapen HD. How to deal with severe acute pancreatitis in the critically ill. Current Opinion in Critical Care. 2019;25(2):150-156. https://doi.org/10.1097/MCC.0000000000000596

Vincent JL. Fluid management in the critically ill. Kidney International. 2019;96(1):52-57. https://doi.org/10.1016/j.kint.2018.11.047

Di Martino M, Van Laarhoven S, Ielpo B, Ramia JM, Manuel-Vázquez A, Martínez-Pérez A, et al. Systematic review and meta-analysis of fluid therapy protocols in acute pancreatitis: type, rate and route. HPB. 2021;23(11):1629-1638. https://doi.org/10.1016/j.hpb.2021.06.426

Kayhan S, Selcan Akyol B, Ergul M, Baysan C. The effect of type of fluid on disease severity in acute pancreatitis treatment. Eur Rev Med Pharmacol Sci. 2021;25(23):7460-7467. https://doi.org/10.26355/eurrev_202112_27443

Leli K, Warren G, Horras S, Bepko J, Longstreet N. Fluid, Electrolyte, and Acid–Base Disorders. In Paulman PM, Taylor RB, Paulman AA, Nasir LS. Family Medicine.: Springer, Cham; 2022. (pp. 1359-1377). https://doi.org/10.1007/978-3-030-54441-6_103

Park CH, Paik WH, Park ET, Shim CS, Lee TY, Kang C, et al. Aggressive intravenous hydration with lactated Ringer’s solution for prevention of post-ERCP pancreatitis: a prospective randomized multicenter clinical trial. Endoscopía. 2018;50(4):378-385. https://doi.org/10.1055/s-0043-122386

Adama T, Van Malenstein H, Laleman W. Meandering main pancreatic duct syndrome: a single-center cohort study and aggregated review. Annals of Gastroenterology. 2024;37:1-8. https://doi.org/10.20524/aog.2024.0901

Published

2025-01-01

How to Cite

Iza-Molina, D. X., & Silvia Tatiana, S. T. (2025). Initial fluid therapy in the treatment of acute pancreatitis. Revista Arbitrada Interdisciplinaria De Ciencias De La Salud. Salud Y Vida, 9(17), 13–32. https://doi.org/10.35381/s.v.v9i17.4334

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Original breve