Clinical manifestations of DiGeorge's syndrome
DOI:
https://doi.org/10.35381/s.v.v8i1.3818Keywords:
DiGeorge syndrome, coronary vessel anomalies, heart defects congenital, (Source: DeCS)Abstract
Objective: To describe the different signs and symptoms of DiGeorge syndrome in order to better understand this disease. Method: Descriptive documentary, 15 articles published in PubMed were analyzed. Conclusion: Within the chromosomal region 22q11.2 several genes have been associated with the phenotypes of congenital anomalies, some of which require surgical procedures depending on the severity of the heart disease. The main cardiac defects with prevalence and percentages of some alterations caused by this syndrome were evidenced, among the most important are the aortic arch, truncus arteriosus and tetralogy of Fallot.
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